منابع مشابه
Alcoholic Liver Disease: Introduction
What is Alcoholic Liver Disease? As the name implies, alcoholic liver disease is liver injury attributed to alcohol abuse. The majority of Americans manage to drink alcohol without serious consequences. Research suggests, however, that liver disease may begin to develop after a "threshold" dose of alcohol has been consumed—generally assumed to be four drinks a day (four 12 ounces beers, four gl...
متن کاملAlcoholic liver disease.
Alcohol is a major cause of liver cirrhosis in the Western world and accounts for the majority of cases of liver cirrhosis seen in district general hospitals in the UK. The three most widely recognised forms of alcoholic liver disease are alcoholic fatty liver (steatosis), acute alcoholic hepatitis, and alcoholic cirrhosis. The exact pathogenesis of alcoholic liver injury is still not clear but...
متن کاملAdvances in alcoholic liver disease.
Alcoholic liver disease (ALD) remains a leading cause of death from liver disease in the United States. In studies from the Veterans Administration, patients with cirrhosis and superimposed alcoholic hepatitis had greater than 60% mortality over a 4-year period, with most of those deaths occurring in the first month. Thus, the prognosis for this disease is more ominous than for many common type...
متن کاملMetabolomics in Alcoholic Liver Disease
Alcoholic liver disease (ALD) is a major cause of morbidity and mortality worldwide among the people with alcohol abuse worldwide. Diagnosis of ALD might be clinically challenging as there is no reliable diagnostic “biomarker” that predict and confirm patients at the risk of ALD. As a new promising “omics” in systems biology, metabolomics provides a useful tool for discovering novel molecular s...
متن کاملAlcoholic liver disease
During the 1950s and '60s when the debate about the relative contribution of alcohol toxicity and malnutrition to alcohol related liver damage was raging in the United States,' Britain was more interested in other forms of liver disease. As awareness ofthe size of the alcohol problem grew in this country,2 3 research work at the Liver Unit began to reflect the changing situation. Immunology was...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2020
ISSN: 2045-2322
DOI: 10.1038/s41598-020-77007-z